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Artificial Life
Book Review: What Is Life?: Investigating the Nature of Life in the Age of Synthetic Biology by Ed Regis


(out of 5 stars)
Philospher and popular science writer Ed Regis takes a modern look at the biological and philosophical nature of defining life in What is Life. While the subject matter is utterly fascinating, and at times this book is quite engaging, there were lots of problems with Regis's presentation.
Right off the bat, Regis sets up his story by detailing the work of researchers seeking to create artificial cells. The work itself is amazing and full of intriguing aspects. However, Regis somehow manages to drag the reader through this section with far-too clinical a look at the business and economic side of the work. While this sort of detail is appropriate in a larger, more comprehensive work, this was a large section of a book with less than 170 pages of actual text.
From there, a long stretch of science history is described, including Schrodinger, Watson, Crick, and others. Far too often for my taste, Regis quotes the brilliant but often highly-criticized Stephen Jay Gould. Gould's views on biology are frequently the subject of harsh criticism from his peers, and while that certainly does not make him incorrect, Regis fails to offer opposing views in situations where Gould's impressions are not necessarily so widely accepted. Regis does this in several other cases as well, in one instance offering a single sentence mentioning Richard Dawkins work, immediately following this by proclaiming that Dawkins's selfish gene theory "hardly settled the issue." Well of course it didn't settle the issue, but that's hardly the point.
Throughout the book, Regis asks us to think about what life is and how we might describe it. He hints early on that his conclusion centers on metabolism. Certainly a reasonable hypothesis, but only rarely does Regis offer actual support for this thesis. At one point, after describing the creation of a synthetic virus, he states: "That itself would have been an example of creating life ... except for the fact that a virus was not a living thing, but rather only a string of dead chemicals inside a protein coating." While that may be one way to describe a virus, this is a skewed interpretation based on Regis's theory that metabolism is absolutely required in a definition of life, a thesis that is not completely agreed upon by biologists or philosophers. Viruses in the wild do appear to have no life-like characteristics, but in vitro they are clearly performing many aspects of replication, mutation, and natural selection. It is hard to say a set of 'dead chemicals' can suddenly transform into something life-like without really explaining to the reader why this is so. Regis drops the ball and offers no explanation.
To be fair, parts of the book are enlightening and enjoyable, including later parts describing the modern work being done in the field of artificial life. But the narrative of history is mediocre, and the author's own philosophy often gets in the way of the story. Three stars.
Artificial Personalities
This is really cool:
The first artificial creature to receive the genomic personality is Rity, a dog-like software character that lives in a virtual 3D world in a PC. Rity’s genome is composed of 14 chromosomes, which together are composed of a total of 1,764 genes, each with its own value. Rather than manually assign the gene values, which would be difficult and time-consuming, the researchers proposed an evolutionary process that generates a genome with a specific personality desired by a user.
Here we have a very neat way of creating complex personalities from a set of finite but numerous input variables. This 'genomic' method of allocating behaviors is not new, but it is facinating where this research is heading. I've long been interested in artificial life and technology-aided genomic behavior, and hope to get involved in a project involving code-based versions of this sort of thing (which a friend and I have modelled, so far, in our heads) in the near future.
"This is the first time that an artificial creature like a robot or software agent has been given a genome with a personality," Kim told PhysOrg.com. "I proposed a new concept of an artificial chromosome as the essence to define the personality of an artificial creature and to pass on its traits to the next generation, like a genetic inheritance. It is critical to provide an impression that the robot is a living creature. With this respect, having emotions enhances natural human-robot interaction for human-robot symbiosis in the coming years."
As the researchers explain, an autonomous artificial creature - whether a physical robot or software agent - can behave, interact, and react to environmental stimuli. Rity, for example, can interact with humans in the physical world using information through a mouse, a camera, or a microphone, with 47 perceptions. For instance, a single click and double click on Rity are perceived as 'patted' and 'hit,' respectively. Dragging Rity slowly and softly is perceived as 'soothed,' and dragging it quickly and wildly as 'shocked.'
To react to these stimuli in real time, Rity relies on its internal states which are composed of three units - motivation, homeostasis, and emotion - and controlled by its internal control architecture. The three units have a total of 14 states, which are the basis of the 14 chromosomes: the motivation unit includes six states (curiosity, intimacy, monotony, avoidance, greed, and the desire to control); the homeostasis unit includes three states (fatigue, hunger, and drowsiness); and the emotion unit has five states (happiness, sadness, anger, fear, and neutral).














































